The demand for DNA synthesizers continues to grow rapidly, and there is a large space for import substitution in the domestic market after 2021

DNA synthesis is a method of artificially connecting deoxyribonucleotides one by one in a predetermined nucleotide sequence to synthesize DNA strands; A DNA synthesizer is an automated instrument used for synthesizing oligonucleotides with structures similar to DNA or RNA. The oligonucleotide products synthesized by DNA synthesizers can be widely used in fields such as point mutations, subcloning, whole gene synthesis, PCR amplification, DNA sequencing, etc. It can save human resources, reduce research and development and production costs for research institutions and enterprises, and improve research and development and production efficiency.

According to the "2021 Global and China DNA Synthesizer Industry Deep Research Report" released by the New World Industry Research Center, DNA synthesizers are an important component of the gene therapy and biopharmaceutical industry chain, and are upstream production equipment. The DNA synthesizer mainly consists of multiple parts, including reagent drive system, reagent bottle group, base bottle group, pressure pipeline and delivery pipeline, phosphorous amide bottle, pressure exhaust pipe, delivery solenoid valve, auxiliary vacuum, synthesis column, path throttle valve, waste liquid bottle, exhaust device, conductivity cell, battery, controller, etc. To ensure the reliability and ****** of the equipment, there are high barriers in the design, research and development, and production of DNA synthesizers.

DNA synthesizers are widely used in life science experiments, biotechnology, biopharmaceuticals, gene therapy and other fields. With the continuous deepening of life science and technology research in China, the scale of industries such as biopharmaceuticals and gene therapy continues to expand. In order to improve production efficiency and reduce production costs, the demand for DNA synthesizers in the Chinese market continues to grow. From 2011 to 2020, the average annual compound growth rate of the DNA synthesizer market in China was 12.4%, showing a rapid upward trend. Gene therapy and biomedicine have become one of the key areas of concern for the development of China's medical industry. It is expected that the demand for DNA synthesizers in China will continue to maintain a rapid growth trend in the next five years.

According to their uses, DNA synthesizers can be divided into three categories: laboratory type synthesizers, industrial type synthesizers, and large-scale synthesis synthesizers. Different types of products can be applied in different application fields. The laboratory type synthesizer has a low synthesis flux and is mainly used in biological laboratories; Industrial synthesizers have a high synthesis flux and are mainly used in large biological laboratories and commercial institutions; The large-scale synthesis synthesizer can be mass-produced and is mainly used in the field of biopharmaceutical raw material preparation. With the rapid development of gene therapy and the biopharmaceutical industry, it is expected that the demand for industrial and large-scale synthetic DNA synthesizers will accelerate in the future.

According to industry analysts from New World, DNA synthesizer manufacturers in the global market mainly include Thermo Fisher from the United States, ABI from the United States, BioAutomation from the United States, GE Health from the United States, Backman Coulter from the United States, TAG COPENHAGEN A/S from Denmark, OligoMaker from Denmark, Pharmacia from Sweden, PolyGen from Germany, and others. China also has the production capacity of DNA synthesizers, but compared with foreign enterprises, due to the overall technology of the industry